Corning® Microcarriers for Bioprocess Scale-up

Corning microcarriers are designed to simplify your scale-up processes. The microcarriers are sterile, ready-to-use, and available in closed systems packaging to be used directly with bioreactors. Additionally, the microcarriers are surface-treated to enhance cell attachment, maximizing cell yield and viability. Corning microcarriers are available sterile and ready to use in 10 g vials. This format provides flexibility to select the amount of beads to use. During the mature phase of process development and into manufacturing, closed system packaging would be necessary to maintain sterility and ease bioreactor loading. Corning microcarriers are also available in off-the-shelf and custom closed systems packaging. Tubing, connectors, and materials are customizable based on individual needs.

• Sterility Assurance Level (SAL) of 10^-6
• Nonpyrogenic
• Available as closed system solutions
• Consistency - USP Class VI polystyrene material provides a consistent platform

Corning microcarriers are offered with four surface treatments:
- Corning Synthemax® II substrate creates a synthetic surface on the microcarriers for stem cell expansion. Use low concentration for MSC applications and high concentration for iPS/ES applications.
- Corning CellBIND® surface treatment infuses the surface of the microcarriers with oxygen to improve cell attachment
- Positive charge surface treatment
- Collagen coating

Specifications:
• Bead size: 125 m to 212 m
• Density: 1.026 +/- 0.004 g/cm³
• cm²/gram: 360
Image(s) are representative of the product group and not necessarily the individual product.

RTU Vial
Surface Treatment: CellBIND
Size: 10 g

RTU Vial
Surface Treatment: Collagen Type I
Size: 10 g

RTU Vial
Surface Treatment: High Concentration Synthemax II
Size: 10 g

RTU Vial
Surface Treatment: Low Concentration Synthemax II
Size: 10 g

RTU Vial
Surface Treatment: Untreated
Size: 10 g

Closed System Packaging
Surface Treatment: CellBIND
Size: 100 g

Closed System Packaging
Surface Treatment: Low Concentration Synthemax II
Size: 100 g

Closed System Packaging
Surface Treatment: Untreated
Size: 100 g

Closed System Packaging
Surface Treatment: CellBIND
Size: 500 g

Closed System Packaging
Surface Treatment: Low Concentration Synthemax II
Size: 500 g

Closed System Packaging
Surface Treatment: Untreated
Size: 500 g