acumedia* Tryptic Soy Broth Modified with Novobiocin and Acid Digest of Casein

• Intended Use: Tryptic Soy Broth, Modified with 20 mg / L Novobiocin & Acid Digest of Casein is used for the selective
enrichment of enterohemorrhagic E. coli in foods. Conforms to USDA Formulation with Novobiocin supplementation.
• Product Summary and Explanation: There are four recognized classes of enterovirulent E. coli that cause gastroenteritis in
humans. Enterohemorrhagic (EHEC) strain designated E. coli O157:H7, makes up one of the four classes. E. coli serotype O157:
H7 is a rare variety of E. coli that produces large quantities of one or more related, potent toxins that cause severe damage to the
lining of the intestine. E. coli O157:H7 infection often cause severe bloody diarrhea and abdominal cramps. The infection can also
cause a complication called Hemolytic Uremic Syndrome (HUS). The toxins destroy red blood cells and can lead to kidney failure.
About 2 - 7% of infections lead to HUS, particularly in children below the age of 5 and the elderly.
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