acumedia* Tryptic Soy Broth Modified with Novobiocin

• Intended Use: Tryptic Soy Broth, Modified with Novobiocin is used for the selective enrichment of enterohemorrhagic E. coli in
foods.
• Product Summary and Explanation: There are four recognized classes of enterovirulent E. coli that cause gastroenteritis in
humans.1 Enterohemorrhagic (EHEC) strain designated E. coli O157:H7, makes up one of the four classes. E. coli serotype
O157:H7 is a rare variety of E. coli that produces large quantities of one or more related, potent toxins that cause severe damage
to the lining of the intestine.1 E. coli O157:H7 infection often cause severe bloody diarrhea and abdominal cramps. The infection
can also cause a complication called Hemolytic Uremic Syndrome (HUS). The toxins destroy red blood cells and can lead to
kidney failure. About 2 - 7% of infections lead to HUS, particularly in children below the age of 5 and the elderly.
Tryptic Soy Broth, Modified with Novobiocin is used to enrich food samples suspected of having low levels of EHEC during
pathogen testing.
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